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When ROS levels exceed the metabolic capacity of active glutathione, cell damage, thrombosis, and acute hemolytic anemia may occur

Protein abundances were quantified using the MaxQuant label-free quantification (LFQ) algorithm [34], which normalizes chromatographic peak integrations

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Dysregulation of iron metabolism in COVID-19-related PD Iron metabolism impairment, a significant contributor to PD [91, 92], has been extensively established in a significant fraction of COVID-19 patients in response to SARS-CoV-2 infection [93,94,95], which corresponds with the risk of severe and fatal COVID-19 illness